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KMID : 0941820040140020071
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Korean Journal of Clinical Pharmacy
2004 Volume.14 No. 2 p.71 ~ p.77
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The Effect of Deoxyribonuclease-Bromelain Tablet in Patients with Inflammation of Otorhinolaryngology
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Park Sung-Yong
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Abstract
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The author has tested the clinical efficacy and safety of an anti-inflammatory drug in patients with inflammation of the otnrhinolaryngology. Deoxyribonuclease prepared from bovine pancreas destroyed fibers and reduced the viscosity of the exudates. Bromelain is a group of proteolytic enzymes which are known to have an effect on inflammation, swelling, and pain in inflammatory disorders. The mucolytic and anti-inflammatory properties of deoxyribonuclease associated with bromelain in inflammation of otorhinolaryngology were assessed in 67 patients. A standard dose of 3 tablets of deoxyribonuclease bromelain tablet was given for not less than 7 days. In all tile groups of patients considered, the drug showed a considerable therapeutic effectiveness. At the end of 7-28 days treatment, more than 89.6% of treatment was improved. These findings suggest that it could be permitted to use deoxyribonuclease-bromelain tablet in patients with inflammation of the otorhinolaryngology.
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KEYWORD
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Deoxyribonuclease, Bromelain, Anti-inflammatory drug
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